Choose the Best Endotoxin Removal

EtoxiClear® – Confidence in Every Purification

Surpass regulatory requirements with confidence

Streamline your processes and reduce time-to-market

Preserve valuable proteins & enhance your end product

Eliminate the costly consequences of endotoxin contamination

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EtoxiClear® is a synthetic ligand affinity adsorbent, designed for the efficient removal of endotoxins from biological preparations. Enhanced with the capability to be depyrogenated using sodium hydroxide, it offers increased flexibility and utility. With its high binding capacity and low protein binding, EtoxiClear® is ideal for a variety of applications, from process development to cGMP manufacturing.

High Affinity for Endotoxin

Versatile

Excellent Protein Recovery

Scalable

Binding capacity in excess of 1,000,000 EU/mL

A wide range of proteins can be processed independent of their iso-electric point.

Up to 95% recovery across pH 4.0 to pH 8.0.

Available in various disposable column sizes for different process scales

Comparative Advantage: Discover the EtoxiClear® Difference in Endotoxin Removal

We put EtoxiClear® to the test against alternative endotoxin removal products, including ion exchange and affinity membrane-based solutions, under standardized protocols and identical starting conditions. The results? EtoxiClear® consistently delivered superior endotoxin clearance and higher protein recovery.

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*equal to or below limit of detection BSS – balanced salt solution

EtoxiClear® excels in a variety of applications where endotoxin removal is critical:

Biopharmaceutical Purification

Cell Culture Media Preparation

Research & Development

Chromatography Resin

Final Polishing

Efficiently removes endotoxins from biopharmaceutical products during downstream processing.

Ensures endotoxin-free buffers for cell culture applications, promoting optimal cell growth and viability.

Ideal for use in small-scale experiments to optimize endotoxin removal processes.

Used in affinity chromatography for high-throughput screening and rapid process development.

Provides a critical final step in purification processes to achieve high purity levels in final products.

Applications for EtoxiClear®

Select Your Ideal EtoxiClear® Solution

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A high-performance, stable affinity chromatography adsorbent for cost-effective and efficient endotoxin removal.

Accelerate your process development and achieve optimal results with these pre-packed, easy-to-use columns for small-scale endotoxin removal.

Miniaturized, pre-packed EtoxiClear® columns for rapid, high-throughput endotoxin removal. Ideal for automation and streamlined workflows.